Technology & Science

We are honoured to present you a special blog edition written by our guest author Dr. Johannes Frasnelli.

Dr. Frasnelli specialises in odor perception. He conducts research in the field of neurophysiology of smell and taste as well as therapy in loss of the chemical senses.

___________________________________________________________________________

This blog follows: On the way to understand how we perceive odors 

For many years neuroscientists have worked in order to determine the basic dimension of odors, or, in other words, to find out in which basic categories we can divide odors into and how we can smell. Sometimes it is helpful to look around a bit, as the world sometimes provides us with wonderful ideas. We can look at perfumers, which are specialists from the point of view how we perceive odors. They use four basic categories for odors. They divide fragrances into the categories “woody”, “fresh”, “oriental”, and “floral”. While these categories may be very useful for perfumers, they are unsatisfactory for a neuroscientist, because there is no corresponding receptor or anatomical structure for these categories. For example, in taste, we can distinguish five (or maybe six) different basic taste qualities. They are sweet, sour, salty, bitter, and umami (and maybe fatty or metallic). These basic tastes however correspond to different receptors – located in the tongue’s mucosa. In the olfactory system, we know that there are hundreds of different receptors. We only know for few of them which odor perception they are responsible for – but there certainly does not appear to be a general distinction into “woody”, “fresh”, “oriental”, and “floral” receptors.

Therefore researchers instead of investigating the nose, started to look more closely at the brain, in order to maybe find anatomical features which may then be linked to odor perception. They indeed found brain regions that respond differently to odor aspects. In fact, they found several aspects of the odors brain regions respond particularly to.

The first of these is the chemical structure of the odorant. Here, researchers let their participants smell several odorants. Some of those odorants smelled like lemon, others smelled like vegetables. The researchers however applied a special trick: in both categories there were odorants which shared chemical properties. Specifically, they used aldehydes and alcohols: some of the aldehydes smelled like lemon, some smelled like vegetables.

images[1] alcohol1[1]

Alcohol group

 Source

 uvu[2]

The same was true for the alcohols: again, some smelled like lemon, some smelled like vegetables. By applying this trick, the researchers could look if there is any brain structure that responds specifically to differences in chemical structure (aldehyde or alcohol) or in odor quality (lemon and vegetable). They were able to find a brain region that specifically responded to chemical structure, and another one, just next to it, that responded specifically to odor quality.

768lemon[1] OLYMPUS DIGITAL CAMERASource: Wikipedia

Another group of researchers was able to determine that there is a brain region that specifically responds to different odor intensities. I have outlined before that odor intensity is also a basic odor category. The same group of researchers also found a brain region that responded to specifically to pleasantness of odors, which therefore may also be one basic odor category. Other categories have been put forward, although there is not yet a brain structure linked to it. For example, edibility of the odor appears to be a basic odor category. This means that an odor which stems from food is fundamentally different from an odor which comes from a non-food odor source.

We have not yet reached a final answer to the question of which is the most basic odor category. There are at least four basic odor categories, namely chemical structure, quality, intensity and odor pleasantness. So, we have some hints towards which direction researchers should look into. From the point of view of a neuroscientist there is not much support for the subdivision of odors into “woody”, “fresh”, “oriental”, and “floral” – other than that perfumers use it.

avec-le-nez[2]

However, the very same perfumers are able to create wonderful scents, so maybe they are right, after all?

Dr. Johannes Frasnelli

Links:

http://ucdenver.edu/academics/colleges/medicalschool/centers/tastesmell/Pages/tastesmell.aspx

http://www.tasteandsmell.com/

en français:

http://www.hcuge.ch/~infotec/rhino/index.htm

 


About the author: Dr. Frasnelli.

Dr. Frasnelli specialises in odor perception. He conducts research in the field of neurophysiology of smell and taste as well as therapy in loss of the chemical senses. Frasnelli is a graduate of the Medical Schools of the University of Vienna (Austria; 2001; Dr. med. univ.) and the Technical University of Dresden (Germany; 2009; Priv.-Doz.). Since 2006 he work in Montreal, first as an Academic Trainee at the Montreal Neurological Institute, since 2008 as a Postdoctoral Fellow at the Department of Psychology at the Université de Montréal. He currently hold a fellowship of the CIHR. Dr. Frasnelli research interest is the neurophysiology of smell and taste as well as therapy in loss of the chemical senses.

Contact information: johannes.frasnelli@umontreal.ca

Personal links:

 

You are curious about the perception and measurement of odors. Discover how does an electronic nose work.

November 1, 2012
odotech

Odor categories: what determines how we can smell?

For many years neuroscientists have worked in order to determine the basic dimension of odors, or, in other words, to find out in which basic categories we can divide odors into and how we can smell. Sometimes it is helpful to look around a bit, as the world sometimes provides us with wonderful ideas. We can look at perfumers, which are specialists from the point of view how we perceive odors. They use four basic categories for odors. They divide fragrances into the categories “woody”, “fresh”, “oriental”, and “floral”.
August 16, 2012
odotech

On the way to understand how we perceive odors

When studying the sense of smell it is always a good idea to look at the other senses as well. Many features in the individual senses have the same characteristics, because evolution and biology is economic. So if we know something about seeing or hearing, then there is a certain chance that the sense of smell works in a similar fashion. And we do know a lot more about seeing or hearing than about smelling.
June 15, 2012
odotech

How Much Odor Control is Enough?

When you spend millions to control odors at a public utility but still get complaints from the neighbors, then what?  Many wastewater treatment plant managers find […]
April 10, 2012
odotech

White paper: WWTP odor control chemical optimization using e-Noses

Odors are a natural byproduct of wastewater treatment, and a problem that has caused no shortage of headaches for cash-strapped public officials. But sanitation engineers in […]
March 30, 2012
Odor Monitoring System OdoWatch

What is an Odor Monitoring System

The approach offers a series of unique advantages over less comprehensive odor detection techniques. Not only do the e-noses provide quantifiable measurements of odor levels at one given location, but the system can use atmospheric dispersion modeling to show the full extent and intensity of an odor plume. An odor monitoring system like OdoWatch combines automatic central monitoring of odor emissions with a clear display showing odor concentration that incorporates current weather data and is updated continuously.